Phosphonate-transporting ATPase

In enzymology, a phosphonate-transporting ATPase (EC 3.6.3.28) is an enzyme that catalyzes the chemical reaction

phosphonate transmembrane-transporting ATPase
Identifiers
EC no.3.6.3.28
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
ATP + H2O + phosphonateout ADP + phosphate + phosphonatein

The 3 substrates of this enzyme are ATP, H2O, and phosphonate, whereas its 3 products are ADP, phosphate, and phosphonate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (phosphonate-transporting).

References

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  • Wanner BL, Metcalf WW (1992). "Molecular genetic studies of a 10.9-kb operon in Escherichia coli for phosphonate uptake and biodegradation". FEMS Microbiol. Lett. 79 (1–3): 133–9. doi:10.1111/j.1574-6968.1992.tb14031.x. PMID 1335942.
  • Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH (1995). "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases". Res. Microbiol. 146 (4): 271–8. doi:10.1016/0923-2508(96)81050-3. PMID 7569321.
  • Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol. Advances in Microbial Physiology. 40: 81–136. doi:10.1016/S0065-2911(08)60130-7. ISBN 9780120277407. PMID 9889977.
  • Griffiths JK; Sansom CE. "The Transporter Factsbook, Academic Press, San Diego, 1998". {{cite journal}}: Cite journal requires |journal= (help)