POP7

Ribonuclease P protein subunit p20 is an enzyme that in humans is encoded by the POP7 gene.

POP7
Identifiers
Aliases	POP7, 0610037N12Rik, RPP2, RPP20, POP7 homolog, ribonuclease P/MRP subunit
External IDs	OMIM: 606113; MGI: 1921347; HomoloGene: 4262; GeneCards: POP7; OMA:POP7 - orthologs
Gene location (Human) Chr. Chromosome 7 (human) Band 7q22.1 Start 100,706,121 bp End 100,707,486 bp
Gene location (Mouse) Chr. Chromosome 5 (mouse) Band 5|5 G2 Start 137,499,700 bp End 137,500,780 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex gastrocnemius muscle gonad right frontal lobe middle temporal gyrus muscle of thigh Brodmann area 9 skin of leg right lobe of liver skin of abdomen Top expressed in otic placode morula otic vesicle interventricular septum blastocyst embryo yolk sac saccule embryo neural tube More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleic acid binding protein binding hydrolase activity RNA binding ribonuclease P activity Cellular component cytoplasm nucleolus nucleus nucleolar ribonuclease P complex nucleoplasm ribonuclease MRP complex multimeric ribonuclease P complex Biological process tRNA processing RNA phosphodiester bond hydrolysis, endonucleolytic tRNA 5'-leader removal RNA phosphodiester bond hydrolysis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10248 74097 Ensembl ENSG00000172336 ENSMUSG00000029715 UniProt O75817 Q9DCH2 RefSeq (mRNA) NM_005837 NM_028753 RefSeq (protein) NP_005828 NP_083029 Location (UCSC) Chr 7: 100.71 – 100.71 Mb Chr 5: 137.5 – 137.5 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Stolc V, Katz A, Altman S (1998). "Rpp2, an essential protein subunit of nuclear RNase P, is required for processing of precursor tRNAs and 35S precursor rRNA in Saccharomyces cerevisiae". Proc. Natl. Acad. Sci. U.S.A. 95 (12): 6716–21. Bibcode:1998PNAS...95.6716S. doi:10.1073/pnas.95.12.6716. PMC 22609. PMID 9618478.
• Jiang T, Altman S (2001). "Protein-protein interactions with subunits of human nuclear RNase P." Proc. Natl. Acad. Sci. U.S.A. 98 (3): 920–5. doi:10.1073/pnas.021561498. PMC 14685. PMID 11158571.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Hua Y, Zhou J (2004). "Rpp20 interacts with SMN and is re-distributed into SMN granules in response to stress". Biochem. Biophys. Res. Commun. 314 (1): 268–76. doi:10.1016/j.bbrc.2003.12.084. PMID 14715275.
• Welting TJ, van Venrooij WJ, Pruijn GJ (2004). "Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex". Nucleic Acids Res. 32 (7): 2138–46. doi:10.1093/nar/gkh539. PMC 407822. PMID 15096576.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

External links

• POP7 human gene location in the UCSC Genome Browser.
• POP7 human gene details in the UCSC Genome Browser.