Pleckstrin homology domain-containing family O member 1 is a protein that in humans is encoded by the PLEKHO1 gene.[5][6]

PLEKHO1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPLEKHO1, CKIP-1, OC120, CKIP1, JBP, pleckstrin homology domain containing O1
External IDsOMIM: 608335; MGI: 1914470; HomoloGene: 9448; GeneCards: PLEKHO1; OMA:PLEKHO1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016274
NM_001304722
NM_001304723
NM_001304724

NM_023320

RefSeq (protein)

NP_001291651
NP_001291652
NP_001291653
NP_057358

NP_075809

Location (UCSC)Chr 1: 150.15 – 150.16 MbChr 3: 95.9 – 95.9 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

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PLEKHO1 has been shown to interact with Casein kinase 2, alpha 1[5] and SMURF1.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000023902Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000015745Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Bosc DG, Graham KC, Saulnier RB, Zhang C, Prober D, Gietz RD, Litchfield DW (May 2000). "Identification and characterization of CKIP-1, a novel pleckstrin homology domain-containing protein that interacts with protein kinase CK2". The Journal of Biological Chemistry. 275 (19): 14295–306. doi:10.1074/jbc.275.19.14295. PMID 10799509.
  6. ^ "Entrez Gene: PLEKHO1 pleckstrin homology domain containing, family O member 1".
  7. ^ Lu K, Yin X, Weng T, Xi S, Li L, Xing G, Cheng X, Yang X, Zhang L, He F (August 2008). "Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1". Nature Cell Biology. 10 (8): 994–1002. doi:10.1038/ncb1760. PMID 18641638. S2CID 19216909.

Further reading

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