Owen Roe (Irish: Eoghan Rua[dh]) most commonly refers to Owen Roe O'Neill (c. 1585–1649), an Irish nobleman and military leader, or to institutions named for him:
- Owen Roe O'Neill's GAC (County Tyrone)
- CLG Eoghan Rua (County Londonderry)
- Eoghan Ruadh, Dungannon GAA
- "The Lament for Owen Roe", ballad
It may also refer to:
- Eoghan Rua Ó Súilleabháin, poet
- Eoghan Ruadh Mac an Bhaird, poet
- Owen Roe McGovern, Gaelic footballer
- Owen Roe (actor)