OR6C3

Olfactory receptor 6C3 is a protein that in humans is encoded by the OR6C3 gene.

OR6C3
Identifiers
Aliases	OR6C3, OST709, olfactory receptor family 6 subfamily C member 3
External IDs	MGI: 3030637; HomoloGene: 105153; GeneCards: OR6C3; OMA:OR6C3 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) Band 12q13.2 Start 55,330,043 bp End 55,332,687 bp
Gene location (Mouse) Chr. Chromosome 10 (mouse) Band 10|10 D3 Start 129,526,490 bp End 129,530,155 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad fundus n/a More reference expression data BioGPS n/a
Gene ontology Molecular function signal transducer activity G protein-coupled receptor activity olfactory receptor activity Cellular component plasma membrane membrane integral component of membrane Biological process signal transduction response to stimulus sensory perception of smell detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 254786 258547 Ensembl ENSG00000205329 ENSMUSG00000046041 UniProt Q9NZP0 Q8VFI3 RefSeq (mRNA) NM_054104 NM_001388498 NM_146554 RefSeq (protein) NP_473445 NP_666765 Location (UCSC) Chr 12: 55.33 – 55.33 Mb Chr 10: 129.53 – 129.53 Mb PubMed search
Wikidata
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Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. Bibcode:2000PNAS...97.2870R. doi:10.1073/pnas.040580197. PMC 16022. PMID 10706615.
• Scherer SE, Muzny DM, Buhay CJ, et al. (2006). "The finished DNA sequence of human chromosome 12". Nature. 440 (7082): 346–51. Bibcode:2006Natur.440..346S. doi:10.1038/nature04569. PMID 16541075.

External links

• OR6C3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.