ADP-sugar pyrophosphatase is an enzyme that in humans is encoded by the NUDT5 gene.[5][6]

NUDT5
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesNUDT5, YSA1, YSA1H, YSAH1, hYSAH1, nudix hydrolase 5, hNUDT5
External IDsOMIM: 609230; MGI: 1858232; HomoloGene: 5388; GeneCards: NUDT5; OMA:NUDT5 - orthologs
EC number3.6.1.58
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014142
NM_001321647
NM_001321648

NM_016918

RefSeq (protein)

NP_001308576
NP_001308577
NP_054861

NP_058614

Location (UCSC)Chr 10: 12.17 – 12.2 MbChr 2: 5.85 – 5.87 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Nudix hydrolases, such as NUDT5, eliminate toxic nucleotide derivatives from the cell and regulate the levels of important signaling nucleotides and their metabolites (McLennan, 1999).[supplied by OMIM][6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000165609Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025817Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ McLennan AG (Aug 1999). "The MutT motif family of nucleotide phosphohydrolases in man and human pathogens (review)". Int J Mol Med. 4 (1): 79–89. doi:10.3892/ijmm.4.1.79. PMID 10373642.
  6. ^ a b "Entrez Gene: NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5".

Further reading

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