Muramasa was a famous Japanese swordsmith who founded the Muramasa school of sword-making in the early 16th century CE.
Muramasa may also refer to:
- Muramasa: The Demon Blade, a 2009 video game for the Wii, later released as Muramasa Rebirth on PS Vita
- Mura Masa, UK electronic music artist
- Muramasa Blade, a fictional sword in Marvel Comics used by Wolverine
- Muramasa, one of the primary antagonists of the anime series Bleach
- Full Metal Daemon: Muramasa, a 2009 visual novel by Nitroplus
- Senji Muramasa, a character in the video game Fate/Grand Order