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MethBase is a database of DNA methylation data derived from next-generation sequencing data.[1] MethBase provides a visualization of publicly available bisulfite sequencing and reduced representation bisulfite sequencing experiments through the UCSC Genome Browser. MethBase contents include single-CpG site resolution methylation levels for each CpG site in the genome of interest, annotation of regions of hypomethylation often associated with gene promoters, and annotation of allele-specific methylation associated with genomic imprinting.
 | |
| Content | |
|---|---|
| Description | Database for single cytosine resolution DNA methylation data and associated annotations. |
| Organisms | Human Chimpanzee Gorilla Rhesus Macaque Mouse Arabidopsis |
| Contact | |
| Laboratory | Andrew D. Smith |
| Primary citation | Qiang Song et al. (2013) [1] |
| Release date | 2013 |
| Access | |
| Data format | Trackhub on the UCSC Genome Browser |
| Website | http://smithlabresearch.org/software/methbase/ |
See also
editReferences
edit- ^ a b Song, Qiang; Decato Benjamin E; Hong Elizabeth; Zhou Meng; Fang Fang; Qu Jianghan; Garvin Tyler; Kessler Michael; Zhou Jun; Smith Andrew D (Dec 2013). "A Reference Methylome Database and Analysis Pipeline to Facilitate Integrative and Comparative Epigenomics". PLOS ONE. 8 (12): e81148. Bibcode:2013PLoSO...881148S. doi:10.1371/journal.pone.0081148. PMC 3855694. PMID 24324667.
External links
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