Matthew C. Keller is an American behavioral and psychiatric geneticist. He is the Director of the Institute for Behavioral Genetics and a professor in the Department of Psychology and Neuroscience at the University of Colorado Boulder.[1] He is known for his criticism of the candidate gene approach [2][3][4] and for development of approaches in quantitative genetics.[5][6]
Matthew C. Keller | |
---|---|
Nationality | American |
Education | University of Texas at Austin University of Michigan |
Scientific career | |
Fields | Behavioral genetics |
Institutions | University of Colorado Boulder |
Thesis | Natural selection and the manifestations of low mood and depression (2004) |
Doctoral advisor | Randolph M. Nesse |
Website | www |
References
edit- ^ "Matthew C Keller's Home Page". www.matthewckeller.com. Retrieved 19 February 2019.
- ^ Duncan, Laramie E.; Keller, Matthew C. (November 2011). "A Critical Review of the First 10 Years of Candidate Gene-by-Environment Interaction Research in Psychiatry". American Journal of Psychiatry. 168 (10): 1041–1049. doi:10.1176/appi.ajp.2011.11020191. ISSN 0002-953X. PMC 3222234. PMID 21890791.
- ^ Border, Richard; Johnson, Emma C.; Evans, Luke M.; Smolen, Andrew; Berley, Noah; Sullivan, Patrick F.; Keller, Matthew C. (May 2019). "No Support for Historical Candidate Gene or Candidate Gene-by-Interaction Hypotheses for Major Depression Across Multiple Large Samples". American Journal of Psychiatry. 176 (5): 376–387. doi:10.1176/appi.ajp.2018.18070881. ISSN 0002-953X. PMC 6548317. PMID 30845820.
- ^ Johnson, Emma C.; Border, Richard; Melroy-Greif, Whitney E.; de Leeuw, Christiaan A.; Ehringer, Marissa A.; Keller, Matthew C. (November 2017). "No Evidence That Schizophrenia Candidate Genes Are More Associated With Schizophrenia Than Noncandidate Genes". Biological Psychiatry. 82 (10): 702–708. doi:10.1016/j.biopsych.2017.06.033. PMC 5643230. PMID 28823710.
- ^ Haplotype Reference Consortium; Evans, Luke M.; Tahmasbi, Rasool; Vrieze, Scott I.; Abecasis, Gonçalo R.; Das, Sayantan; Gazal, Steven; Bjelland, Douglas W.; de Candia, Teresa R.; Goddard, Michael E.; Neale, Benjamin M. (May 2018). "Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits". Nature Genetics. 50 (5): 737–745. doi:10.1038/s41588-018-0108-x. ISSN 1061-4036. PMC 5934350. PMID 29700474.
- ^ Keller, Matthew C. (January 2014). "Gene × Environment Interaction Studies Have Not Properly Controlled for Potential Confounders: The Problem and the (Simple) Solution". Biological Psychiatry. 75 (1): 18–24. doi:10.1016/j.biopsych.2013.09.006. PMC 3859520. PMID 24135711.
External links
edit- Official website
- Faculty page
- Matthew C. Keller publications indexed by Google Scholar