Limestone Canyon virus (LSC) is a single-stranded, negative-sense RNA zoonotic Orthohantavirus that is genetically similar to Sin Nombre orthohantavirus which causes Hantavirus pulmonary syndrome (HPS) in humans. HPS causing hantaviruses are found only in the United States and South America.[1]
| Limestone Canyon virus | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Negarnaviricota |
| Class: | Ellioviricetes |
| Order: | Bunyavirales |
| Family: | Hantaviridae |
| Genus: | Orthohantavirus (?) |
| Virus: | Limestone Canyon virus
|
LSC has not been shown to cause HPS in humans.[2]
Reservoir
editThe virus was isolated from the brush mouse (Peromyscus boylii).[3] Phylogenetic analysis of M genome segment showed LSC to be very distinct from other Peromyscus-borne viruses. Other Peromyscus-associated hantaviruses include Sin Nombre orthohantavirus (SNV), New York orthohantavirus (NYV), and Monongahela virus (MGLV).[1]
See also
editReferences
edit- ^ a b Sanchez AJ, Abbott KD, Nichol ST. Genetic identification and characterization of limestone canyon virus, a unique Peromyscus-borne hantavirus. Virology. 2001 Aug 1;286(2):345–53.
- ^ "DHS Guidelines for rodent hantavirus surveillance" (PDF). Archived from the original (PDF) on 2012-11-13. Retrieved 2013-07-11.
- ^ "ICTV 9th Report (2011) Bunyaviridae". International Committee on Taxonomy of Viruses (ICTV). Retrieved 7 March 2019.
External links
edit- Sloan Science and Film / Short Films / Muerto Canyon by Jen Peel 29 minutes
- "Hantaviruses, with emphasis on Four Corners Hantavirus" by Brian Hjelle, M.D., Department of Pathology, School of Medicine, University of New Mexico
- CDC's Hantavirus Technical Information Index page
- Viralzone: Hantavirus
- Virus Pathogen Database and Analysis Resource (ViPR): Bunyaviridae
- Occurrences and deaths in North and South America