Laura Marie Machesky FRSE FMedSci (born 13 August 1965) is a British-American cancer research scientist. She is the Sir William Dunn Professor of Biochemistry in the Department of Biochemistry, University of Cambridge, and the current president of the British Society for Cell Biology.
Early life and education
editMachesky was born on 13 August 1965 in Dearborn, Michigan, United States. She studied at Alma College, graduating with a Bachelor of Science (BSc) degree in 1987, and then at Johns Hopkins University School of Medicine where she completed her Doctor of Philosophy (PhD) degree in 1993.[1]
Career
editMachesky was a postdoc at the MRC Laboratory of Molecular Biology (LMB) from 1995 to 1997 and then an MRC Career Development Fellow, MRC Senior Research Fellow and Professor of Cell Biology at the School of Biosciences, University of Birmingham from 1998 to 2007.[2][3][4] She was a Medical Research Council (MRC) senior research fellow and Professor of Cell Biology at the Beatson Institute for Cancer Research in Glasgow from 2007 to 2022, and director of the Institute of Cancer Sciences at the University of Glasgow from 2020 to 2022. She moved to Cambridge University in 2022 as Sir William Dunn Professor of Biochemistry.[1]
Research interests
editMachesky's research group specialises in cancer cell migration, invasion, metastasis and the energetics of cell biology. She discovered the 7-subunit Arp2/3 complex and showed that this was a major regulator of actin dynamics and cell migration. According to the Academy of Medical Sciences, this work "changed the way the field understood fundamental principles of signalling to actin dynamics and impacted on biomedical problems such as host-pathogen interactions, endocytic trafficking, phagocytosis and cancer cell invasion".[4]
Awards and honours
editMachesky was elected as a Member of the European Molecular Biology Organisation in 2012,[5] a Fellow of the Royal Society of Edinburgh in 2014,[3] and a Fellow of the Academy of Medical Sciences in 2016.[4] Her husband Robert Insall is also a Fellow of the Royal Society of Edinburgh and a professor at the University of Glasgow.[6]
References
edit- ^ a b "Machesky, Prof. Laura Marie, (born 13 Aug. 1965), Sir William Dunn Professor of Biochemistry, since 2022, and Co-Chair, Engineering Biology Interdisciplinary Research Centre, since 2022, University of Cambridge; Fellow, Robinson College, Cambridge, since 2022". Who's Who 2024. Oxford University Press. 1 December 2023. Retrieved 2 November 2024.
- ^ Milbourne, Dr S. (16 January 2023). "Laura Machesky". www.mrc-tox.cam.ac.uk. Retrieved 14 July 2023.
- ^ a b "Professor Laura Marie Machesky FRSE, FMedSci". The Royal Society of Edinburgh. 24 August 2020. Retrieved 16 September 2020.
- ^ a b c "Professor Laura Machesky | The Academy of Medical Sciences". acmedsci.ac.uk. Retrieved 16 September 2020.
- ^ Katja. "Find a member". EMBO. Retrieved 16 September 2020.
- ^ "Couple have become fellows". Glasgow Times. Retrieved 24 May 2021.