John Michael Sedivy is the Hermon C. Bumpus Professor of Biology and a professor of Medical Science at Brown University. He is listed as a F1000 Prime faculty member and on Who's Who in Gerontology. He has published over 130 original articles.[1]
John Sedivy | |
|---|---|
| Academic background | |
| Education | |
| Academic work | |
| Institutions | Brown University |
He wrote the first book on gene targeting in 1992.[2] In 2006, he published the first comprehensive in vivo quantification of cellular senescence in aging primates. That year, his lab also discovered how (through the Polycomb pathway) c-Myc contributes to the regulation of chromatin states. His research has found that mice missing one copy of the Myc transcription factor live longer than wild-type mice.[3]
He is co-Editor-in-Chief of the journal Aging Cell, and is chair of the 2015 Gordon Research Conference on the Biology of Aging.
Bibliography
editBooks
edit- Sedivy, J. M., & Joyner, A. L. (1992). Gene targeting. WH Freeman and company. ISBN 9780195099683
Selected publications
edit- Sedivy, J. M., & Sharp, P. A. (1989). Positive genetic selection for gene disruption in mammalian cells by homologous recombination. Proceedings of the National Academy of Sciences, 86(1), 227–231.
Awards
edit- 1974 Ontario Scholar
- 1981 Ryan Foundation Fellow
- 1989 March of Dimes Basil O'Connor Starter Scholar
- 1990 Presidential Young Investigator
- 1991 Andrew Mellon Award
- 2006 Hermon C. Bumpus Endowed Chair in Biology, Brown University
- 2007 Senior Research Scholar in Aging, Ellison Medical Foundation
- 2009 NIH MERIT Award, National Institute on Aging
- 2011 Glenn Award for Research in Biological Mechanisms of Aging
- 2015 Chair, Gordon Research Conference on the Biology of Aging
References
edit
- ^ Researchers at Brown Profile
- ^ Gene Targeting
- ^ "Benefits of Missing MYC". The Scientist Magazine®.