Ioxilan

Ioxilan
Clinical data
Trade names	Oxilan
AHFS/Drugs.com	FDA Professional Drug Information
Routes of; administration	intravenously
ATC code	V08AB12 (WHO) ;
Legal status
Legal status	US: ℞-only; Discontinued;
Pharmacokinetic data
Bioavailability	N/A
Protein binding	negligible
Metabolism	none
Elimination half-life	2 hours
Excretion	Mostly renal
Identifiers
	IUPAC name 1-N-(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-3-N-(2-hydroxyethyl)-2,4,6-triiodobenzene-1,3-dicarboxamide;
CAS Number	107793-72-6 ;
PubChem CID	3743;
DrugBank	DB09135 ;
ChemSpider	3612 ;
UNII	A4YJ7J11TG;
KEGG	D02161 ;
ChEMBL	ChEMBL1201075 ;
CompTox Dashboard (EPA)	DTXSID0048717 ;
Chemical and physical data
Formula	C18H24I3N3O8
Molar mass	791.116 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(N(c1c(I)c(c(I)c(c1I)C(=O)NCCO)C(=O)NCC(O)CO)CC(O)CO)C;
	InChI InChI=1S/C18H24I3N3O8/c1-8(28)24(5-10(30)7-27)16-14(20)11(17(31)22-2-3-25)13(19)12(15(16)21)18(32)23-4-9(29)6-26/h9-10,25-27,29-30H,2-7H2,1H3,(H,22,31)(H,23,32) ; Key:UUMLTINZBQPNGF-UHFFFAOYSA-N ;
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Ioxilan is a diagnostic contrast agent.^[1] It is injected intravenously before taking X-ray images to increase arterial contrast in the final image. It was marketed in the US under the trade name Oxilan by Guerbet, L.L.C., but was discontinued in 2017.^[2]

Mechanism of action

Ioxilan is an iodinated contrast agent.^[2]

References

^ Cheng KT (December 2007). "Ioxilan carbonate particles". Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US). PMID 20641969.
^ ^a ^b Oxilan FDA Professional Drug Information. Accessed 2021-04-07.

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[pmid20641969-1] Cheng KT (December 2007). "Ioxilan carbonate particles". Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US). PMID 20641969.

[drugs.com-2] Oxilan FDA Professional Drug Information. Accessed 2021-04-07.

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