Indolelactate dehydrogenase

In enzymology, an indolelactate dehydrogenase (EC 1.1.1.110) is an enzyme that catalyzes the chemical reaction

indolelactate dehydrogenase
Identifiers
EC no.1.1.1.110
CAS no.37250-41-2
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IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
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(indol-3-yl)lactate + NAD+ (indol-3-yl)pyruvate + NADH + H+

Thus, the two substrates of this enzyme are (indol-3-yl)lactate and NAD+, whereas its 3 products are (indol-3-yl)pyruvate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (indol-3-yl)lactate:NAD+ oxidoreductase. This enzyme is also called indolelactate:NAD+ oxidoreductase. This enzyme participates in tryptophan metabolism.

References

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  • Jean M, DeMoss RD (1968). "Indolelactate dehydrogenase from Clostridium sporogenes". Can. J. Microbiol. 14 (4): 429–35. doi:10.1139/m68-068. PMID 4384683.