INO80 complex subunit B is a protein that in humans is encoded by the INO80B gene. [5]
INO80B | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | INO80B, HMGA1L4, HMGIYL4, IES2, PAP-1BP, PAPA-1, ZNHIT4, hIes2, PAPA1, INO80 complex subunit B | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 616456; MGI: 1917270; HomoloGene: 32566; GeneCards: INO80B; OMA:INO80B - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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![](http://up.wiki.x.io/wikipedia/commons/thumb/3/30/INO80_stabilizes_replication_forks_and_counteracts_mislocalization_of_H2A.Z.png/220px-INO80_stabilizes_replication_forks_and_counteracts_mislocalization_of_H2A.Z.png)
Function
editThis gene encodes a subunit of an ATP-dependent chromatin remodeling complex, INO80, which plays a role in DNA and nucleosome-activated ATPase activity and ATP-dependent nucleosome sliding. Readthrough transcription of this gene into the neighboring downstream gene, which encodes WW domain-binding protein 1, generates a non-coding transcript.
References
edit- ^ a b c GRCh38: Ensembl release 89: ENSG00000115274 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030034 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: INO80 complex subunit B". Retrieved 2016-12-13.
Further reading
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.