The hepatitis E virus cis-reactive element is an RNA element that is believed to be essential for "some step in gene expression".[1] The mutation of this element resulted in hepatitis E strains which were unable to infect rhesus macaques (Macaca mulatta).[1]
| Hepatitis E virus cis-reactive element | |
|---|---|
 Predicted secondary structure and sequence conservation of HepE_CRE | |
| Identifiers | |
| Symbol | HepE_CRE |
| Rfam | RF00550 |
| Other data | |
| RNA type | Cis-reg |
| Domain(s) | Viruses |
| SO | SO:0000233 |
| PDB structures | PDBe |
References
edit- ^ a b Graff J, Nguyen H, Yu C, Elkins WR, St Claire M, Purcell RH, Emerson SU (June 2005). "The open reading frame 3 gene of hepatitis E virus contains a cis-reactive element and encodes a protein required for infection of macaques". Journal of Virology. 79 (11): 6680–6689. doi:10.1128/JVI.79.11.6680-6689.2005. PMC 1112134. PMID 15890906.
External links
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