HOT-17 (2,5-dimethoxy-4-(β-isobutylthio)-N-hydroxyphenethylamine) is a psychedelic phenethylamine of the 2C family. It was synthesized by Alexander Shulgin and reported in his book PiHKAL.[1]

HOT-17
Names
Preferred IUPAC name
2-{4-[(Butan-2-yl)sulfanyl]-2,5-dimethoxyphenyl}-N-hydroxyethan-1-amine
Other names
2-[4-(Isobutylthio)-2,5-dimethoxyphenyl]ethanaminol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C14H23NO3S/c1-5-10(2)19-14-9-12(17-3)11(6-7-15-16)8-13(14)18-4/h8-10,15-16H,5-7H2,1-4H3 checkY
    Key: BUKIXGXYEUJJHQ-UHFFFAOYSA-N checkY
  • InChI=1/C14H23NO3S/c1-5-10(2)19-14-9-12(17-3)11(6-7-15-16)8-13(14)18-4/h8-10,15-16H,5-7H2,1-4H3
    Key: BUKIXGXYEUJJHQ-UHFFFAOYAH
  • CC(CC)Sc1cc(OC)c(cc1OC)CCNO
Properties
C14H23NO3S
Molar mass 285.40 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemistry

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HOT-17's full chemical name is 2-[4-(2-isobutylthio)-2,5-dimethoxyphenyl-N-hydroxyethanamine. It has structural properties similar to 2C-T-17 and to other drugs in the HOT- series, with the most closely related compounds being HOT-2 and HOT-7.

General information

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The dosage range of HOT-17 is typically 70-120 mg and its duration is approximately 12–18 hours according to Shulgin.[1] HOT-17 produces time distortion and general psychedelia. It also has little to no body load.

See also

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References

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