Frank Osborne may refer to:
- Frank Osborne (California politician), mayor of Alameda, California
- Frank Osborne (footballer) (1896–1988), English footballer
- Frank I. Osborne (1853–1920), North Carolina politician
- Frank M. Osborne (1879–1956), college football player and coach
See also
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This disambiguation page lists articles about people with the same name.
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