Epidural steroid injection (ESI) is a technique in which corticosteroids and a local anesthetic are injected into the epidural space around the spinal cord in an effort to improve spinal stenosis, spinal disc herniation, or both. It is of benefit with a rare rate of major side effects.[1][2]
Epidural steroid injection | |
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Specialty | Pain medicine |
Medical uses
editEpidural steroid injection for sciatica and spinal stenosis is of unclear effect.[1] The evidence to support use in the cervical spine is not very good.[3] When medical imaging is not used to determine the proper spot for injection, ESI benefits appear to be of short-term benefit when used in sciatica.[4] It is unclear if ESI is useful for chronic pain after spinal surgery.[5]
Side effects
editMajor side effects are rare.[2] These include loss of vision, stroke, paralysis, or death when the corticosteroids are infected, as in a 2012 meningitis outbreak.[2][6] Another study found an increased odds of developing epidural lipomatosis, independent of body mass index (BMI) or other factors.[7]
Technique
editElective spinal injections should be performed with imaging guidance, such as fluoroscopy or the use of a radiocontrast agent, unless that guidance is contraindicated.[8] Imaging guidance ensures the correct placement of the needle and maximizes the physician's ability to make an accurate diagnosis and administer effective therapy.[8] Without imaging, the risk increases for the injection to be incorrectly placed, and this would in turn lower the therapy's efficacy and increase subsequent risk of need for more treatment.[8]
References
edit- ^ a b Shaughnessy, AF (15 February 2016). "Epidural Steroid Not Better Than Placebo Injection for Sciatica and Spinal Stenosis Pain and Function". American Family Physician. 93 (4): 315–6. PMID 26926820.
- ^ a b c Schneider, B; Zheng, P; Mattie, R; Kennedy, DJ (August 2016). "Safety of epidural steroid injections". Expert Opinion on Drug Safety. 15 (8): 1031–9. doi:10.1080/14740338.2016.1184246. PMID 27148630. S2CID 27053083.
- ^ Cohen, SP; Hooten, WM (14 August 2017). "Advances in the diagnosis and management of neck pain". BMJ (Clinical Research Ed.). 358: j3221. doi:10.1136/bmj.j3221. PMID 28807894. S2CID 29500924.
- ^ Vorobeychik, Y; Sharma, A; Smith, CC; Miller, DC; Stojanovic, MP; Lobel, SM; Valley, MA; Duszynski, B; Kennedy, DJ; Standards Division of the Spine Intervention, Society (December 2016). "The Effectiveness and Risks of Non-Image-Guided Lumbar Interlaminar Epidural Steroid Injections: A Systematic Review with Comprehensive Analysis of the Published Data". Pain Medicine (Malden, Mass.). 17 (12): 2185–2202. doi:10.1093/pm/pnw091. PMID 28025354.
- ^ Wylde, V; Dennis, J; Beswick, AD; Bruce, J; Eccleston, C; Howells, N; Peters, TJ; Gooberman-Hill, R (September 2017). "Systematic review of management of chronic pain after surgery". The British Journal of Surgery. 104 (10): 1293–1306. doi:10.1002/bjs.10601. PMC 5599964. PMID 28681962.
- ^ Kauffman, CA; Malani, AN (April 2016). "Fungal Infections Associated with Contaminated Steroid Injections". Microbiology Spectrum. 4 (2): 359–374. doi:10.1128/microbiolspec.EI10-0005-2015. ISBN 978-1-55581-944-6. PMID 27227303. S2CID 42550449.
- ^ Jaimes, Rafael; Rocco, Angelo (August 2014). "Multiple epidural steroid injections and body mass index linked with occurrence of epidural lipomatosis: a case series". BMC Anesthesiology. 14 (70): 70. doi:10.1186/1471-2253-14-70. PMC 4145583. PMID 25183952.
- ^ a b c North American Spine Society (February 2013), "Five Things Physicians and Patients Should Question", Choosing Wisely: an initiative of the ABIM Foundation, North American Spine Society, retrieved 25 March 2013