Eastman is a surname. Notable people with the surname include:
- A. Theodore Eastman, American bishop
- Allan Eastman (1912–1987), Australian diplomat
- Annis Bertha Ford Eastman (1852–1910), American Congregationalist minister
- Arthur Macarthur Eastman (1810–1877), American industrialist
- Ben C. Eastman (1812–1856), American politician, U.S. representative from Wisconsin (1851–1855)
- Benjamin Franklin Eastman (1800–1894), American politician in Maine
- Carole Eastman (1934–2004), American screenwriter
- Charles Eastman (1858–1939), Native American physician, writer, national lecturer and reformer
- Charles R. Eastman (1868–1918), American palaeontologist
- Charles S. Eastman (1864-1939) American lawyer and politician
- Creswell Eastman (b.1940) Australian endocrinologist, professor of medicine, known for Iodine Deficiency Disorders research.
- Crystal Eastman (1881–1928) American lawyer, anti-militarist, feminist, socialist and journalist
- David Eastman, (b. 1945) Australian convicted murderer
- David Eastman (politician)
- Edward Eastman, American politician
- Enos Eastman (1821–1908), American politician from Wisconsin
- George Eastman (1854–1932), American inventor and philanthropist, founder of Kodak
- George Eastman (actor) (b. 1942), Italian actor
- H. E. Eastman (1819–1898), American politician, 3rd mayor of Green Bay, Wisconsin
- Howard Eastman (b. 1970), middleweight boxer
- Irene Eastman (1894–1918), American singer, daughter of Charles Eastman
- John A. Eastman, Wisconsin politician
- John C. Eastman (b. 1960), American lawyer, law professor and politician
- John H. Eastman (1861–1938), Louisiana politician
- Joseph Bartlett Eastman (1882–1944), American government official in various capacities
- Julius Eastman (1940–1990), African-American composer, pianist, vocalist and dancer
- Kevin Eastman (b. 1962), co-creator of the Teenage Mutant Ninja Turtles series
- Kevin Eastman (basketball) (born 1955), American basketball player and coach, currently assistant to Los Angeles Clippers head coach Doc Rivers
- La Fayette Eastman (1819–1898), American politician from Wisconsin
- Lee Eastman (1910–1991), American attorney and art collector
- Leroy D. Eastman (1872-1945), American politician
- Linda McCartney née Eastman (1941–1998), American photographer, musician and animal rights activist, wife of Paul McCartney, daughter of Lee Eastman
- Linda Eastman (1867–1963), American librarian
- Marilyn Eastman (1933–2021), American actress
- Marvin Eastman (b. 1971), American mixed martial artist and kickboxer
- Mary Eastman, American singer
- Mary F. Eastman (1833-1908), American educator, lecturer, writer, suffragist
- Mary H. Eastman (1818–1887), born Mary Henderson; American writer on Native American life; wife of Seth
- Max Eastman (1883–1969), American writer, poet and political activist
- Monk Eastman (1875–1920), New York gangster
- P. D. Eastman (1909–1986), cartoonist and author of children's books
- Peter Eastman (disambiguation)
- Rebecca Lane Hooper Eastman (1877–1937), American writer
- Rodney Eastman (b. 1967), Canadian actor
- Seth Eastman (1808–1875), US Army officer, mapmaker and illustrator; husband of Mary H.
- Seth and Mary Eastman (1808–1875 and 1818–1887), recorders of Native American life
- W. Dean Eastman (b. 1948), American educator