dCMP deaminase (EC 3.5.4.12, deoxycytidylate deaminase, deoxy-CMP-deaminase, deoxycytidylate aminohydrolase, deoxycytidine monophosphate deaminase, deoxycytidine-5'-phosphate deaminase, deoxycytidine-5'-monophosphate aminohydrolase) is an enzyme which converts deoxycytidylic acid to deoxyuridylic acid.[1][2][3]

dCMP deaminase
Deoxycytidylate deaminase hexamer, Cyanophage s-tim5
Identifiers
EC no.3.5.4.12
CAS no.9026-92-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
dCMP deaminase
Identifiers
SymbolDCTD
NCBI gene1635
HGNC2710
OMIM607638
RefSeqNM_001921
UniProtP32321
Other data
EC number3.5.4.12
LocusChr. 4 q35.1
Search for
StructuresSwiss-model
DomainsInterPro

References

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  1. ^ Scarano E (March 1960). "The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. I. The enzymatic deamination of deoxycytidine 5'-phosphate and of 5-methyldeoxycytidine 5-methyldeoxycytidine 5'-phosphate". The Journal of Biological Chemistry. 235 (3): 706–13. doi:10.1016/S0021-9258(19)67927-5. PMID 14442222.
  2. ^ Scarano E, Bonaduce L (December 1960). "The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. II. Purification and properties of a 6-aminopyrimidine deoxyribonucleoside 5'-phosphate deaminase from unfertilized eggs of sea urchine". The Journal of Biological Chemistry. 235 (12): 3556–61. doi:10.1016/S0021-9258(18)64507-7. PMID 13747062.
  3. ^ Sergott RC, Debeer LJ, Bessman MJ (December 1971). "On the regulation of a bacterial deoxycytidylate deaminase". The Journal of Biological Chemistry. 246 (24): 7755–8. doi:10.1016/S0021-9258(19)45839-0. PMID 5002683.
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