The enzyme cyanide hydratase (EC 4.2.1.66) catalyzes the chemical reaction
| cyanide hydratase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.1.66 | ||||||||
| CAS no. | 37292-83-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- formamide cyanide + H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is formamide hydro-lyase (cyanide-forming). Other names in common use include formamide dehydratase, and formamide hydro-lyase.[1] This enzyme participates in cyanoamino acid metabolism.
References
edit- ^ Gupta, Neha; Balomajumder, Chandrajit; Agarwal, V. K. (2010-04-15). "Enzymatic mechanism and biochemistry for cyanide degradation: A review". Journal of Hazardous Materials. 176 (1): 1–13. doi:10.1016/j.jhazmat.2009.11.038. ISSN 0304-3894.
- Fry WE, Millar RL (1972). "Cyanide degradion by an enzyme from Stemphylium loti". Arch. Biochem. Biophys. 151 (2): 468–74. doi:10.1016/0003-9861(72)90523-1. PMID 5065258.
