Cubero is the surname of:
- Vicente Aguilar Cubero (1808–1861), Costa Rican politician
- Edwin Cubero (1924–2000), Costa Rican footballer
- Fabián Cubero (born 1978), Argentine footballer
- Jhonny Cubero (born 1976), Costa Rican footballer
- Jonathan Cubero (born 1994), Uruguayan footballer
- José Cubero Sánchez El Yiyo (1964–1985), Spanish bullfighter
- José Miguel Cubero (born 1987), Costa Rican footballer
- Pedro Cubero (1645-c. 1697), Spanish priest and world traveler
- Ruben A. Cubero (born 1939), United States Air Force brigadier general
- Vicente Cubero (guerilla) (1911–1942), Filipino World War II guerilla leader
- Linda Garcia Cubero (born 1958), first Hispanic woman to graduate from any U.S. military service academy
- José María Movilla Cubero (born 1975), Spanish footballer