Crotonyl-CoA reductase

Crotonyl-CoA reductase (EC 1.3.1.86, butyryl-CoA dehydrogenase, butyryl dehydrogenase, unsaturated acyl-CoA reductase, ethylene reductase, enoyl-coenzyme A reductase, unsaturated acyl coenzyme A reductase, butyryl coenzyme A dehydrogenase, short-chain acyl CoA dehydrogenase, short-chain acyl-coenzyme A dehydrogenase, 3-hydroxyacyl CoA reductase, butanoyl-CoA:(acceptor) 2,3-oxidoreductase, CCR) is an enzyme with systematic name butanoyl-CoA:NADP+ 2,3-oxidoreductase.[1] This enzyme catalyses the following chemical reaction

Crotonyl-CoA reductase
Identifiers
EC no.1.3.1.86
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins
butanoyl-CoA + NADP+ (E)-but-2-enoyl-CoA + NADPH + H+

This enzyme catalyses the reaction in the reverse direction.

References

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  1. ^ Wallace KK, Bao ZY, Dai H, Digate R, Schuler G, Speedie MK, Reynolds KA (November 1995). "Purification of crotonyl-CoA reductase from Streptomyces collinus and cloning, sequencing and expression of the corresponding gene in Escherichia coli". European Journal of Biochemistry. 233 (3): 954–62. doi:10.1111/j.1432-1033.1995.954_3.x. PMID 8521864.
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