(Robert) Charles Swanton FRS FMedSci FRCP is British physician scientist specialising in oncology and cancer research. Swanton is a senior group leader at London's Francis Crick Institute,[3] Royal Society Napier Professor in Cancer[4] and thoracic medical oncologist at University College London[5] and University College London Hospitals,[6][7] co-director of the Cancer Research UK (CRUK) Lung Cancer Centre of Excellence, and Chief Clinician of Cancer Research UK.[8][9]
Charles Swanton | |
---|---|
![]() Swanton in 2018 | |
Born | Robert Charles Swanton 1972 (age 51–52)[2] |
Education | St Paul's School, London |
Alma mater | University College London (MD, PhD) |
Awards | Ellison–Cliffe Lecture (2017) EMBO Member (2017) |
Scientific career | |
Fields | Cancer evolution[1] |
Institutions | Francis Crick Institute University College London |
Thesis | Viral cyclin disruption of mammalian cell cycle control mechanisms (1998) |
Doctoral advisor | Nic Jones |
Website | www |
Early life and education
editThis section needs expansion. You can help by adding to it. (June 2024) |
Swanton was born in Poole, Dorset. As of 2017, his father Robert Howard Swanton (MD, FRCP) was a consultant cardiologist at UCL.[10]
Swanton was educated at St Paul's School, London[2] and completed his PhD in 1999[11] at what was then the Imperial Cancer Research Fund Laboratories (now the Francis Crick Institute) and his Cancer Research UK clinician scientist/medical oncology training in 2008.[7]
Career
editSwanton has combined [when?] his laboratory research with clinical duties as co-director of the CRUK Lung Cancer Centre, focussed on how tumours evolve over space and time.[7] He has helped to define the branched evolutionary histories of solid tumours, processes that drive cancer cell-to-cell variation in the form of new cancer mutations or chromosomal instabilities, and the impact of such cancer diversity on effective immune surveillance and clinical outcome.[1][7][12][13]
As of 2018, Swanton has been a co-founder of Achilles Therapeutics[14] with Sergio Quezada, Karl Peggs and Mark Lowdell. Achilles Therapeutics is a UCL/CRUK and Francis Crick Institute[15] biotechnology company funded by Syncona[16] that develops adoptive T cell therapies targeting clonal/truncal neo-antigens present in every tumour cell to limit drug resistance and tumour evolution.[citation needed]
Awards and honours
edit- 1997: Imperial Cancer Research Fund's (ICRF) Pontecorvo PhD thesis prize[17]
- 2011: Fellow of the Royal College of Physicians (FRCP)[citation needed]
- 2014: Jeremy Jass Prize in pathology
- 2015: Fellow of the Academy of Medical Sciences (FMedSci)[18]
- 2015: Stand up to Cancer Translational Cancer Research Prize
- 2016: Glaxo Smithkline Biochemical Society Prize[citation needed]
- 2016: San Salvatore prize for Cancer Research[19]
- 2017: CRUK Translational Research Prize in 2017,[20]
- 2017: EMBO Member in 2017[21]
- 2017: Ellison-Cliffe Medal by the Royal Society of Medicine
- 2018: Elected a Fellow of the Royal Society (FRS)[7]
- 2018: Massachusetts General Hospital Cancer Centre Kraft Prize[22]
- 2018: Gordon Hamilton Fairley Medal and Lecture[7][23]
- 2019: ESMO Translational Research Award
- 2020: Addario Lung Cancer Foundation Award and Lecture
- 2021: Weizmann Institute - Sergio Lambroso Award in Cancer Research
- 2021: Paul Marks Prize for Cancer Research
Personal life
editThis section needs expansion. You can help by adding to it. (June 2024) |
References
edit- ^ a b Charles Swanton publications indexed by Google Scholar
- ^ a b c Anon (2017). "Swanton, Prof. (Robert) Charles". Who's Who (online Oxford University Press ed.). Oxford: A & C Black. doi:10.1093/ww/9780199540884.013.U286524. (Subscription or UK public library membership required.)
- ^ "Charles Swanton – The Francis Crick Institute". crick.ac.uk.
- ^ Anon (2016). "Leading scientists awarded Royal Society Research Professorships". royalsociety.org. Royal Society. Retrieved 27 November 2018.
- ^ "Iris View Profile". iris.ucl.ac.uk. Archived from the original on 22 May 2017. Retrieved 12 January 2022.
- ^ "The UCLH lung cancer service". uclh.nhs.uk. Retrieved 27 November 2018.
- ^ a b c d e f Anon (2018). "Professor Charles Swanton FMedSci FRS". London: Royal Society. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
"All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." --"Terms, conditions and policies | Royal Society". Archived from the original on 11 November 2016. Retrieved 27 June 2018.
{{cite web}}
: CS1 maint: bot: original URL status unknown (link) - ^ "Chief Executive and Executive Board". 27 September 2013.
- ^ Charles Swanton publications from Europe PubMed Central
- ^ Anon (2017). "Swanton, Robert Howard". Who's Who (online Oxford University Press ed.). Oxford: A & C Black. doi:10.1093/ww/9780199540884.013.U4000216. (Subscription or UK public library membership required.)
- ^ Swanton, Robert Charles (1998). Viral cyclin disruption of mammalian cell cycle control mechanisms. london.ac.uk (PhD thesis). University College London (University of London). OCLC 941060556. EThOS uk.bl.ethos.286205.
- ^ Swanton, Charles; Mann, David J.; Fleckenstein, Bernhard; Neipel, Frank; Peters, Gordon; Jones, Nic (1997). "Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins". Nature. 390 (6656): 184–187. Bibcode:1997Natur.390..184S. doi:10.1038/36606. ISSN 0028-0836. PMID 9367157. S2CID 4397584.
- ^ Charles Swanton publications indexed by the Scopus bibliographic database. (subscription required)
- ^ "Our Team – Achilles Therapeutics". achillestx.com. Retrieved 27 November 2018.
- ^ UCL (5 October 2016). "UCL spin-out Achilles Therapeutics to develop immunotherapies for cancer". UCL News. Retrieved 27 November 2018.
- ^ "Achilles Therapeutics". Syncona. Retrieved 27 November 2018.
- ^ "Pontecorvo Prize for best PhD thesis". cancerresearchuk.org. 28 October 2015. Retrieved 27 November 2018.
- ^ "Professor Charles Swanton – The Academy of Medical Sciences". acmedsci.ac.uk. Retrieved 27 November 2018.
- ^ Systems, eZ. "List of Award Winners / Fondazione San Salvatore". fondazionesansalvatore.ch. Archived from the original on 22 July 2018. Retrieved 27 November 2018.
- ^ "Translational Cancer Research Prize". cancerresearchuk.org. 28 October 2015. Retrieved 27 November 2018.
- ^ Jukic, Igor. "EMBO welcomes 65 new members". Embo.org. Archived from the original on 27 September 2017. Retrieved 27 November 2018.
- ^ "Kraft Prize Symposium – Massachusetts General Hospital, Boston, MA". massgeneral.org. Retrieved 27 November 2018.
- ^ Azvolinsky, Anna (2018). "Cancer Evolutionist: A Profile of Charles Swanton". The Scientist.
This article incorporates text available under the CC BY 4.0 license.