Cervical conization refers to an excision of a cone-shaped portion of tissue from the mucous membrane of the cervix. Conization is used for diagnostic purposes as part of a biopsy and for therapeutic purposes to remove pre-cancerous cells (cervical intraepithelial neoplasia) or early stage cervical cancer.[1]
| Cervical conization | |
|---|---|
| ICD-9-CM | 67.2 |
- Cold knife conization (CKC)
- Laser conization
- Loop electrical excision procedure (LEEP)
Side effects
editCervical conization effectively reduces the risk of cancer developing or spreading but it causes an increased risk of premature birth in future pregnancies.[2][3]
The chances of cancer recurrence and premature birth depends on the type of conization. Cold knife conization is associated with 7% chance of the cancer recurring and 16% chance of premature birth, laser conisation comes with 6% cancer recurrence and 13% premature birth, and loop excision comes with 10% recurrence and 11% premature birth.[2][3]
See also
editReferences
edit- ^ Cooper, Danielle B.; Carugno, Jose; Menefee, Gary W. (2023), "Conization of Cervix", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 28722875, retrieved 2023-11-16
- ^ a b c Athanasiou, Antonios; Veroniki, Areti Angeliki; Efthimiou, Orestis; Kalliala, Ilkka; Naci, Huseyin; Bowden, Sarah; Paraskevaidi, Maria; Arbyn, Marc; Lyons, Deirdre; Martin-Hirsch, Pierre; Bennett, Phillip; Paraskevaidis, Evangelos; Salanti, Georgia; Kyrgiou, Maria (2022-07-25). "Comparative effectiveness and risk of preterm birth of local treatments for cervical intraepithelial neoplasia and stage IA1 cervical cancer: a systematic review and network meta-analysis". The Lancet Oncology. 23 (8): 1097–1108. doi:10.1016/S1470-2045(22)00334-5. PMC 9630146. PMID 35835138.
- ^ a b c "Prevention of cervical cancer: what are the risks and benefits of different treatments?". NIHR Evidence (Plain English summary). National Institute for Health and Care Research. 2023-11-10. doi:10.3310/nihrevidence_60599. S2CID 265201829.
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