CHAMP1

Chromosome alignment-maintaining phosphoprotein 1 (CHAMP1) also known as zinc finger protein 828 (ZNF828) is a protein that in humans is encoded by the CHAMP1 gene.

CHAMP1
Identifiers
Aliases	CHAMP1, C13orf8, CAMP, CHAMP, ZNF828, MRD40, chromosome alignment maintaining phosphoprotein 1
External IDs	OMIM: 616327; MGI: 1196398; HomoloGene: 18780; GeneCards: CHAMP1; OMA:CHAMP1 - orthologs
Gene location (Human) Chr. Chromosome 13 (human) Band 13q34 Start 114,314,482 bp End 114,337,626 bp
Gene location (Mouse) Chr. Chromosome 8 (mouse) Band 8 A1.1|8 6.4 cM Start 13,919,641 bp End 13,931,639 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of ileum secondary oocyte ganglionic eminence epithelium of colon tibialis anterior muscle cardiac muscle tissue of right atrium thymus skin of thigh myocardium of left ventricle stromal cell of endometrium Top expressed in hand zygote oocyte secondary oocyte primary oocyte otolith organ utricle maxillary prominence epiblast primitive streak More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding metal ion binding nucleic acid binding Cellular component cytoplasm chromosome spindle chromosome, centromeric region cytoskeleton condensed chromosome nucleus kinetochore nucleoplasm Flemming body Biological process sister chromatid biorientation protein localization to microtubule attachment of mitotic spindle microtubules to kinetochore protein localization to kinetochore Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 283489 101994 Ensembl ENSG00000198824 ENSMUSG00000047710 UniProt Q96JM3 Q8K327 RefSeq (mRNA) NM_032436 NM_001164144 NM_001164145 NM_181854 NM_001363455 RefSeq (protein) NP_001157616 NP_001157617 NP_115812 NP_862902 NP_001350384 Location (UCSC) Chr 13: 114.31 – 114.34 Mb Chr 8: 13.92 – 13.93 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

External links

• CHAMP1 UK - Charity for those affected by CHAMP1 disorders.
• CHAMP1 Research Foundation - Non-Profit raising funds for research into CHAMP1 and CHAMP1 disorders.
• Human CAMP genome location and CAMP gene details page in the UCSC Genome Browser.
• Human CHAMP1 genome location and CHAMP1 gene details page in the UCSC Genome Browser.

Further reading

• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (October 2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
• Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (August 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Nagase T, Nakayama M, Nakajima D, Kikuno R, Ohara O (April 2001). "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 8 (2): 85–95. doi:10.1093/dnares/8.2.85. PMID 11347906.