Bowenoid papulosis is a cutaneous condition characterized by the presence of pigmented verrucous papules on the body of the penis.[1]: 730 [2]: 408 They are associated with human papillomavirus, the causative agent of genital warts.[3]
| Bowenoid papulosis | |
|---|---|
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| Specialty | Dermatology  |
The term bowenoid papulosis was coined in 1977 by Kopf and Bart and is named after dermatologist John Templeton Bowen.[4][5][6]
Signs and symptoms
editBowenoid papulosis is defined by the appearance of one or more reddish-brown papules or plaques in the anogenital region that can last for a few weeks to several years. Although some patients occasionally report itching in relation to affected perianal skin areas, the majority of individuals do not exhibit any symptoms.[7]
Causes
editAlthough the exact cause of bowenoid papulosis is unknown, immunologic, viral, and chemical factors have all been proposed. There have been multiple occurrences of bowenoid papulosis where HPV DNA was found.[8]
Diagnosis
editBowenoid papulosis diagnosis requires a history, histologic examination, and clinical description of the condition.[9]
Treatment
editBowenoid papulosis is typically treated with locally destructive or ablative therapies, including 5-fluorouracil, electrocoagulation, cryotherapy, and surgical excision or razor excision. Imiquimod has also been applied with good results.[10]
See also
editReferences
edit- ^ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
- ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 978-0-7216-2921-6.
- ^ Goorney BP, Polori R (December 2004). "A case of bowenoid papulosis of the penis successfully treated with topical imiquimod cream 5%". Int J STD AIDS. 15 (12): 833–5. doi:10.1258/0956462042563774. PMID 15601490. S2CID 22765485.
- ^ synd/3996 at Who Named It?
- ^ Kopf AW, Bart RS (1977). "Tumor conference No. 11: multiple bowenoid papules of the penis: a new entity?". The Journal of Dermatologic Surgery and Oncology. 3 (3): 265–9. doi:10.1111/j.1524-4725.1977.tb00289.x. PMID 874134.
- ^ Wade TR, Kopf AW, Ackerman AB (October 1978). "Bowenoid papulosis of the penis". Cancer. 42 (4): 1890–903. doi:10.1002/1097-0142(197810)42:4<1890::AID-CNCR2820420430>3.0.CO;2-C. PMID 361215.
- ^ IACOBUZIO-DONAHUE, CHRISTINE A. (2009). "Inflammatory and Neoplastic Disorders of the Anal Canal". Surgical Pathology of the GI Tract, Liver, Biliary Tract, and Pancreas. Elsevier. pp. 733–761. doi:10.1016/b978-141604059-0.50031-x. ISBN 978-1-4160-4059-0.
- ^ Ro, Jae Y.; Kim, Kyu-Rae; Amin, Mahul B.; Ayala, Alberto G. (2008). "Penis and scrotum". Urologic Surgical Pathology. Elsevier. pp. 890–950. doi:10.1016/b978-0-323-01970-5.50017-8. ISBN 978-0-323-01970-5.
- ^ Gross, G. (1990). "Bowenoid Papulosis". Genital Papillomavirus Infections. Berlin, Heidelberg: Springer Berlin Heidelberg. pp. 189–207. doi:10.1007/978-3-642-75723-5_14. ISBN 978-3-642-75725-9.
- ^ Weedon, David (2010). "Viral diseases". Weedon's Skin Pathology. Elsevier. p. 607–631.e22. doi:10.1016/b978-0-7020-3485-5.00027-9. ISBN 978-0-7020-3485-5.
Further reading
edit- Patterson, James W.; Kao, Grace F.; Graham, James H.; Helwig, Elson B. (1986-02-15). "Bowenoid papulosis: A clinicopathologic study with ultrastructural observations". Cancer. 57 (4): 823–836. doi:10.1002/1097-0142(19860215)57:4<823::AID-CNCR2820570424>3.0.CO;2-3. ISSN 0008-543X. PMID 3002589.
- Nayak, Sudhir U. K.; Shenoi, Shrutakirthi D.; Bhat, Shaila T.; Shivamurthy, Archana (2024-03-14). "Bowenoid papulosis". Indian Journal of Sexually Transmitted Diseases and AIDS. 36 (2). Wolters Kluwer -- Medknow Publications: 223–225. doi:10.4103/0253-7184.167196. PMC 4660577. PMID 26692627.