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Look up Big Smoke in Wiktionary, the free dictionary.
The Big Smoke may refer to:
- London, England
- Toronto, Canada
- Big Smoke Burger, an international restaurant chain based in Toronto, Ontario, Canada
- Jack Johnson (boxer), referred to as "Big Smoke"
- "The Big Smoke", a book about Johnson by Adrian Matejka
- Melvin "Big Smoke" Harris, the secondary antagonist in Grand Theft Auto: San Andreas
- The Big Smoke (publication), an Australian opinion site, also with an American version
- The Big Smoke (novel), a 1959 novel by Australian writer D'Arcy Niland