Anne Brunet (born on November 8)[1] is a French geneticist who is the Michele and Timothy Barakett Endowed Professor and the co-director of the Paul F. Glenn Laboratories for the Biology of Aging at Stanford University School of Medicine. Her lab studies mechanisms of aging and longevity.[2]

Anne Brunet
Born
Alma materEcole Normale Supérieure, BS and University of Nice, PhD
Scientific career
FieldsGenetics, aging
InstitutionsStanford University School of Medicine
Doctoral advisorDacques Pouysségur
Websiteweb.stanford.edu/group/brunet/index.html

Personal life

edit

Brunet is from Bellegarde sur Valserine, France, uses red wine as an anti-aging strategy, and plays piano and violin.[1]

Education

edit

Brunet received her BS in biology in 1992 from Ecole Normale Supérieure, Paris, France. She immediately began a PhD in the lab of Jacques Pouysségur at the University of Nice, France, which she completed in 1997. Between 1998 and 2003, she did her postdoctoral work at Harvard Medical School in Michael E. Greenberg's laboratory. She has been a professor at Stanford since 2004.[3] She is a member of the editorial board for Genes & Development.[4]

Research

edit

Brunet's lab works on discovering lifespan-regulating genes and their interactions with the environment. Next, she studies how conserved 'pro-longevity genes' (e.g. FOXO transcription factors) regulate longevity in mammals, the regenerative potential of stem cells, and the nervous system. She uses mammalian tissue culture and C. elegans as model systems to study longevity pathways, dietary restriction, and epigenetic (chromatin-state) regulation of longevity by the environment. In addition, she is developing the extremely short-lived African killifish N. furzeri as a new vertebrate model for aging.[1][5]

The Chan Zuckerberg Initiative awarded a $525,000 research grant to Brunet, along with colleagues Ami Bhatt and K. Christopher Garcia, for their project "Analyzing how inflammation affects the aging brain."[6]

Brunet received the 2022 Lurie Prize in Biomedical Sciences in recognition of work showing "how specific biochemical modifications of the protein structures around which an organism’s DNA is organized can extend its life and that of its descendants".[7]

References

edit
  1. ^ a b c "Brunet Lab: Molecular Basis of Longevity and Age Related Diseases". web.stanford.edu.
  2. ^ "Anne Brunet - Stanford Medicine Profiles". med.stanford.edu.
  3. ^ "CV" (PDF). web.stanford.edu.
  4. ^ "Genes & Development -- Genes & Development Editorial Board".
  5. ^ FranceinSF (12 December 2011). "Interview d'Anne Brunet - Chercheuse a Stanford" – via YouTube.
  6. ^ News, Stanford. "Chan Zuckerberg Initiative awards $1.49 million to Stanford researchers | The Dish". news.stanford.edu. Retrieved 2021-01-02. {{cite web}}: |last= has generic name (help)
  7. ^ "2022 Winners of the FNIH Lurie Prize in Biomedical Sciences Provide Powerful Contributions to Our Understanding of the Aging Process". fnih.org. 14 April 2022.
edit