In enzymology, an allantoinase (EC 3.5.2.5) is an enzyme that catalyzes the chemical reaction
allantoinase | |||||||||
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![]() Allantoinase (analog) tetramer, Pseudomonas fluorescens | |||||||||
Identifiers | |||||||||
EC no. | 3.5.2.5 | ||||||||
CAS no. | 9025-20-1 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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- (S)-allantoin + H2O allantoate
Thus, the two substrates of this enzyme are (S)-allantoin and H2O, whereas its product is allantoate.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amides. The systematic name of this enzyme class is (S)-allantoin amidohydrolase. This enzyme participates in purine metabolism.
References
edit- Florkin, Duchateau-Bosson G (1940). "Microdosage photometrique de l'allantoine en solutions pures et dans l'urine". Enzymologia. 9: 5–9.