Abbas Khan may refer to:
- Abbas Khan, Lorestan, a village in Kashkan Rural District, Lorestan Province, Iran
- Abbas Khan (cricketer) (1911–2002), Indian cricketer
- Abbas Khan (squash player) (1954–2021), Pakistani squash player
- Abbas Khan (died 2013), British orthopaedic surgeon killed while imprisoned by the Syrian government, see Death of Abbas Khan