MPAA (4-Mercaptophenylacetic acid) is a redox buffer that increases the folding rate of disulfide-containing proteins.
Names | |
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IUPAC name
2-(4-sulfanylphenyl)acetic acid
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Preferred IUPAC name
(4-Sulfanylphenyl)acetic acid | |
Other names
2-(4-Mercaptophenyl)acetic acid
4-Mercaptophenylacetic acid MPAA | |
Identifiers | |
3D model (JSmol)
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ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.156.056 |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
HSC6H4CH2CO2H | |
Molar mass | 168.21 g/mol |
Hazards | |
GHS labelling: | |
Danger | |
H315, H318, H319, H335 | |
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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MPAA is also used in native chemical ligation as a thiol catalyst.