(3S,6E)-nerolidol synthase (EC 4.2.3.48, (E)-nerolidol synthase, nerolidol synthase, (3S)-(E)-nerolidol synthase, FaNES1) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((3S,6E)-nerolidol-forming).[1][2][3][4] This enzyme catalyses the following chemical reaction
| (3S,6E)-nerolidol synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.48 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (2E,6E)-farnesyl diphosphate + H2O (3S,6E)-nerolidol + diphosphate
The enzyme catalyses a step in the formation of (3E)-4,8-dimethylnona-1,3,7-triene.
References
edit- ^ Aharoni A, Giri AP, Verstappen FW, Bertea CM, Sevenier R, Sun Z, Jongsma MA, Schwab W, Bouwmeester HJ (November 2004). "Gain and loss of fruit flavor compounds produced by wild and cultivated strawberry species". The Plant Cell. 16 (11): 3110–31. doi:10.1105/tpc.104.023895. PMC 527202. PMID 15522848.
- ^ Bouwmeester HJ, Verstappen FW, Posthumus MA, Dicke M (September 1999). "Spider mite-induced (3S)-(E)-nerolidol synthase activity in cucumber and lima bean. The first dedicated step in acyclic C11-homoterpene biosynthesis". Plant Physiology. 121 (1): 173–80. doi:10.1104/pp.121.1.173. PMC 59365. PMID 10482672.
- ^ Degenhardt J, Gershenzon J (April 2000). "Demonstration and characterization of (E)-nerolidol synthase from maize: a herbivore-inducible terpene synthase participating in (3E)-4,8-dimethyl-1,3,7-nonatriene biosynthesis". Planta. 210 (5): 815–22. doi:10.1007/s004250050684. PMID 10805454. S2CID 798627.
- ^ Arimura G, Garms S, Maffei M, Bossi S, Schulze B, Leitner M, Mithöfer A, Boland W (January 2008). "Herbivore-induced terpenoid emission in Medicago truncatula: concerted action of jasmonate, ethylene and calcium signaling". Planta. 227 (2): 453–64. doi:10.1007/s00425-007-0631-y. PMC 2756395. PMID 17924138.
External links
edit- (3S,6E)-nerolidol+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
