Æthelflæd /ˈæθəlflæd/ is an Anglo-Saxon female name meaning "noble beauty". Notable people with the name include:
- Æthelflæd, Lady of the Mercians, daughter of Alfred the Great
- Æthelflæd of Damerham, queen of England, second wife of King Edmund and mother of Edward II
- Æthelflæd Eneda, first wife of King Edgar and mother of Edward the Martyr
- Abbess Ælflæda of Romsey (Ethelflaeda), saint and daughter of Edward the Elder
- Abbess Æthelflæda of Romsey, 11th century abbess