Vestibulocochlear nerve

Vestibulocochlear nerve
Vestibulocochlear nerve
	The course and connections of the facial nerve in the temporal bone
	Inferior view of the human brain, with the cranial nerves labelled.
Details
To	Cochlear nerve, vestibular nerve
Innervates	Hearing, balance
Identifiers
Latin	nervus vestibulocochlearis
MeSH	D000159
NeuroNames	553
TA98	A14.2.01.121
TA2	6307
FMA	50869
	Anatomical terms of neuroanatomy [edit on Wikidata]

The vestibulocochlear nerve or auditory vestibular nerve, also known as the eighth cranial nerve, cranial nerve VIII, or simply CN VIII, is a cranial nerve that transmits sound and equilibrium (balance) information from the inner ear to the brain. Through olivocochlear fibers, it also transmits motor and modulatory information from the superior olivary complex in the brainstem to the cochlea.^[1]

Structure

The vestibulocochlear nerve consists mostly of bipolar neurons and splits into two large divisions: the cochlear nerve and the vestibular nerve.

Cranial nerve 8, the vestibulocochlear nerve, goes to the middle portion of the brainstem called the pons (which then is largely composed of fibers going to the cerebellum). The 8th cranial nerve runs between the base of the pons and medulla oblongata (the lower portion of the brainstem). This junction between the pons, medulla, and cerebellum that contains the 8th nerve is called the cerebellopontine angle. The vestibulocochlear nerve is accompanied by the labyrinthine artery, which usually branches off from the anterior inferior cerebellar artery at the cerebellopontine angle, and then goes with the 7th nerve through the internal acoustic meatus to the internal ear.

The cochlear nerve travels away from the cochlea of the inner ear where it starts as the spiral ganglia. Processes from the organ of Corti conduct afferent transmission to the spiral ganglia. It is the inner hair cells of the organ of Corti that are responsible for activation of afferent receptors in response to pressure waves reaching the basilar membrane through the transduction of sound. The exact mechanism by which sound is transmitted by the neurons of the cochlear nerve is uncertain; the two competing theories are place theory and temporal theory.

The vestibular nerve travels from the vestibular system of the inner ear. The vestibular ganglion houses the cell bodies of the bipolar neurons and extends processes to five sensory organs. Three of these are the cristae located in the ampullae of the semicircular canals. Hair cells of the cristae activate afferent receptors in response to rotational acceleration. The other two sensory organs supplied by the vestibular neurons are the maculae of the saccule and utricle. Hair cells of the maculae in the utricle activate afferent receptors in response to linear acceleration, while hair cells of the maculae in the saccule respond to vertically directed linear force.

Development

The vestibulocochlear nerve is derived from the embryonic otic placode.

Function

This is the nerve along which the sensory cells (the hair cells) of the inner ear transmit information to the brain. It consists of the cochlear nerve, carrying details about hearing, and the vestibular nerve, carrying information about balance. It emerges from the pontomedullary junction and exits the inner skull via the internal acoustic meatus in the temporal bone.

The vestibulocochlear nerve carries axons of type special somatic afferent.

Clinical significance

Symptoms of damage

Damage to the vestibulocochlear nerve may cause the following symptoms:

hearing loss
vertigo
false sense of motion
loss of equilibrium (in dark places)
nystagmus
motion sickness
gaze-evoked tinnitus.^[2]

Examination

Examinations that can be done include the Rinne and Weber tests.

Rinne's test involves Rinne's Right and Left Test, since auditory acuity is equal in both ears. If bone conduction (BC) is more than air conduction (AC) (BC>AC) indicates Rinne Test is negative or abnormal. If AC>BC Rinne test is normal or positive. If BC>AC and Weber's test lateralizes to abnormal side then it is Conductive hearing loss. If AC>BC and Weber's test lateralizes to normal side then it concludes Sensorineural hearing loss.

After pure-tone testing, if the AC and BC responses at all frequencies 500–8000 Hz are better than 25 dB HL, meaning 0-24 dB HL, the results are considered normal hearing sensitivity. If the AC and BC are worse than 25 dB HL at any one or more frequency between 500 and 8000 Hz, meaning 25+, and there is a no bigger difference between AC and BC beyond 10 dB at any frequency, there is a sensori-neural hearing loss present. If the BC responses are normal, 0-24 dB HL, and the AC are worse than 25 dB HL, as well as a 10 dB gap between the air and bone responses, a conductive hearing loss is present. {updated March 2019}

The modified Hughson–Westlake method is used by many audiologists during testing. A battery of (1) otoscopy, to view the ear canal and tympanic membrane, (2) tympanometry, to assess the immittance of the tympanic membrane and how well it moves, (3) otoacoustic emissions, to measure the response of the outer hair cells located in the cochlea, (4) audiobooth pure-tone testing, to obtain thresholds to determine the type, severity, and pathology of the hearing loss present, and (5) speech tests, to measure the patients recognition and ability to repeat the speech heard, is all taken into consideration when diagnosing the pathology of the patient.

History

Etymology

Some older texts call the nerve the acoustic or auditory nerve,^[3] but these terms have fallen out of widespread use because they fail to recognize the nerve's role in the vestibular system. Vestibulocochlear nerve is therefore preferred by most.

References

^ Lopez-Poveda, Enrique A. (26 March 2018). "Olivocochlear Efferents in Animals and Humans: From Anatomy to Clinical Relevance". Frontiers in Neurology. 9: 197. doi:10.3389/fneur.2018.00197. PMC 5879449. PMID 29632514.
^ Coad, ML; Lockwood, A; Salvi, R; Burkard, R (2001). "Characteristics of patients with gaze-evoked tinnitus". Otology & Neurotology. 22 (5): 650–4. doi:10.1097/00129492-200109000-00016. PMID 11568674. S2CID 44391826.
^ "IX. Neurology. 5h. The Acoustic Nerve. Gray, Henry. 1918. Anatomy of the Human Body". www.bartleby.com. 20 October 2022.

Additional images

Vestibulocochlear nerve
Superficial dissection of brain-stem. Ventral view.
Dissection showing the projection fibers of the cerebellum.
Hind- and mid-brains; postero-lateral view.
Upper part of medulla spinalis and hind- and mid-brains; posterior aspect, exposed in situ.
Position of the right bony labyrinth of the ear in the skull, viewed from above.
Vestibulo-ocular reflex
Vestibulocochlear nerve