Thiotaurine is a bioactive analog of taurine.[1] It is used as a moisturizer and antioxidant in some cosmetic products.[2]

Thiotaurine
Names
IUPAC name
2-Aminoethanethiosulfonic acid
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.019.017 Edit this at Wikidata
EC Number
  • 220-918-7
MeSH C051160
UNII
  • InChI=1S/C2H7NO2S2/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)
    Key: SHWIJIJNPFXOFS-UHFFFAOYSA-N
  • InChI=1/C2H7NO2S2/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)
    Key: SHWIJIJNPFXOFS-UHFFFAOYAT
  • C(CS(=O)(=S)O)N
Properties
C2H7NO2S2
Molar mass 141.20 g·mol−1
Melting point 213-214 °C
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Preparation

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Thiotaurine is made by transsulfuration of thiocysteine and hypotaurine.[3]

References

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  1. ^ Mathew, E; Barletta, MA; Lau-Cam, CA (2013). "The Effects of Taurine and Thiotaurine on Oxidative Stress in the Aorta and Heart of Diabetic Rats". Taurine 8. Advances in Experimental Medicine and Biology. Vol. 775. pp. 345–69. doi:10.1007/978-1-4614-6130-2_28. ISBN 978-1-4614-6129-6. PMID 23392947.
  2. ^ PubChem. "Thiotaurine". pubchem.ncbi.nlm.nih.gov. Retrieved 2022-04-25.
  3. ^ Baseggio Conrado, Alessia; Capuozzo, Elisabetta; Mosca, Luciana; Francioso, Antonio; Fontana, Mario (2019), Hu, Jianmin; Piao, Fengyuan; Schaffer, Stephen W.; El Idrissi, Abdeslem (eds.), "Thiotaurine: From Chemical and Biological Properties to Role in H2S Signaling", Taurine 11, vol. 1155, Singapore: Springer Singapore, pp. 755–771, doi:10.1007/978-981-13-8023-5_66, ISBN 978-981-13-8022-8, PMID 31468446, S2CID 201675446, retrieved 2022-04-25