3α,5α-Tetrahydrocorticosterone (3α,5α-THB), or simply tetrahydrocorticosterone (THB or THCC), is an endogenous glucocorticoid hormone.[1]
Names | |
---|---|
IUPAC name
3α,11β,21-Trihydroxy-5β-pregnan-20-one
| |
Systematic IUPAC name
1-[(1S,3aS,3bS,5aR,7R,9aS,9bS,10S,11aS)-7,10-Dihydroxy-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2-hydroxyethan-1-one | |
Other names
3α,5α-Tetrahydrocorticosterone; 5β-Pregnane-3α,11β,21-triol-20-one
| |
Identifiers | |
3D model (JSmol)
|
|
ChemSpider | |
ECHA InfoCard | 100.000.627 |
PubChem CID
|
|
UNII | |
CompTox Dashboard (EPA)
|
|
| |
| |
Properties | |
C21H34O4 | |
Molar mass | 350.499 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
See also
editReferences
edit- ^ McInnes KJ, Kenyon CJ, Chapman KE, et al. (May 2004). "5alpha-reduced glucocorticoids, novel endogenous activators of the glucocorticoid receptor". The Journal of Biological Chemistry. 279 (22): 22908–12. doi:10.1074/jbc.M402822200. PMID 15044432.