Tartaglia may refer to:
- Tartaglia (commedia dell'arte), commedia dell'arte stock character
- Angelo Tartaglia (1350 or 1370–1421), Italian condottiero
- Nicolo Tartaglia (1499/1500–1557), Venetian mathematician and engineer
- Ivo Tartaglia (1880–1949), Yugoslav politician
- Marino Tartaglia (1894–1984), Croatian painter
- Warren Tartaglia (1944–1965), American jazz musician
- Philip Tartaglia (1951–2021), Roman Catholic Archbishop of Glasgow, Scotland
- Antonio Tartaglia (born 1968), Italian bobsledder
- John Tartaglia (born 1978), American singer, actor, dancer, and puppeteer
- Tartaglia (Chinese: 达达利亚), a playable character in Genshin Impact