Myrtecaine (Nopoxamine), sold as a combination product with diethylamine salicylate under the trade name Algesal and Algésal Suractivé among others, is a local anaesthetic in the form of a topical cream,[2] or with laurilsulfate in rubefacient preparations.[3] It is used to treat muscle strains, tendinitis or ligament sprains and joint pain.[2][3][4] It is a surface anaesthetic, adds to the analgesic and anti-inflammatory actions of diethylamine salicylate by facilitating its penetration.[5] Also myrtecaine has a muscle relaxant effect.[2]

Myrtecaine
Clinical data
Trade namesAlgesal, Algésal Suractivé
Other namesNopoxamine[1]
ATC code
  • none
Identifiers
  • 2-[2-(6,6-Dimethyl-2-bicyclo[3.1.1]hept-2-enyl)ethoxy]-N,N-diethylethanamine
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
CompTox Dashboard (EPA)
ECHA InfoCard100.028.851 Edit this at Wikidata
Chemical and physical data
FormulaC17H31NO
Molar mass265.441 g·mol−1
3D model (JSmol)
  • CCN(CC)CCOCCC1=CCC2CC1C2(C)C
  • InChI=1S/C17H31NO/c1-5-18(6-2)10-12-19-11-9-14-7-8-15-13-16(14)17(15,3)4/h7,15-16H,5-6,8-13H2,1-4H3
  • Key:BZRYYBWNOUALTQ-UHFFFAOYSA-N

References

edit
  1. ^ "Myrtecaine". PubChem. National Center for Biotechnology Information, U.S. National Library of Medicine. Retrieved 2020-08-22.
  2. ^ a b c "Algesal-Creme" (in German). Bundesamt für Sicherheit im Gesundheitswesen. December 2017.
  3. ^ a b "Myrtecaine". Drugster.org.
  4. ^ Elks J, Ganellin CR (1990). "Myrtecaine M-00475". Dictionary of drugs: chemical data, structures, and bibliographies (1st ed.). Dordrecht: Springer. p. 844. ISBN 978-1-4757-2085-3.
  5. ^ "Algesal Cream - Patient Information Leaflet" (PDF). Chemipharm Pharmaceutical Industries, Inc.