In enzymology, a kynurenine-glyoxylate transaminase (EC 2.6.1.63) is an enzyme that catalyzes the chemical reaction:
| kynurenine-glyoxylate transaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.6.1.63 | ||||||||
| CAS no. | 74506-33-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- L-kynurenine + glyoxylate 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine
Thus, the two substrates of this enzyme are L-kynurenine and glyoxylate, whereas its two products are 4-(2-aminophenyl)-2,4-dioxobutanoate and glycine.
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-kynurenine:glyoxylate aminotransferase (cyclizing). This enzyme is also called kynurenine-glyoxylate aminotransferase.
References
edit- Harada I (1980). "[Glucagen inducible kynurenine aminotransferase.]". Wakayama Igaku. 31: 61–68.
