External transcribed spacer

External transcribed spacer (ETS) refers to a piece of non-functional RNA, closely related to the internal transcribed spacer, which is situated outside structural ribosomal RNAs (rRNA) on a common precursor transcript.^[1] ETS sequences characteristic to an organism can be used to trace its phylogeny.^[2]

Organization of the eukaryotic nuclear ribosomal DNA tandem repeats.

References

^ Schibler, U.; Wyler, T.; Hagenbuchle, O. (1975). "Changes in size and secondary structure of the ribosomal transcription unit during vertebrate evolution". Journal of Molecular Biology. 94 (3): 503–17. doi:10.1016/0022-2836(75)90217-X. PMID 809590.
^ Baldwin, B. G.; Markos, S. (1998). "Phylogenetic utility of the external transcribed spacer (ETS) of 18S-26S rDNA: Congruence of ETS and ITS trees of Calycadenia (Compositae)". Molecular Phylogenetics and Evolution. 10 (3): 449–63. doi:10.1006/mpev.1998.0545. PMID 10051397.

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[1] Schibler, U.; Wyler, T.; Hagenbuchle, O. (1975). "Changes in size and secondary structure of the ribosomal transcription unit during vertebrate evolution". Journal of Molecular Biology. 94 (3): 503–17. doi:10.1016/0022-2836(75)90217-X. PMID 809590.

[2] Baldwin, B. G.; Markos, S. (1998). "Phylogenetic utility of the external transcribed spacer (ETS) of 18S-26S rDNA: Congruence of ETS and ITS trees of Calycadenia (Compositae)". Molecular Phylogenetics and Evolution. 10 (3): 449–63. doi:10.1006/mpev.1998.0545. PMID 10051397.

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