In enzymology, a D-methionine—pyruvate transaminase (EC 2.6.1.41) is an enzyme that catalyzes the chemical reaction
| D-methionine-pyruvate transaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.6.1.41 | ||||||||
| CAS no. | 37277-93-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- D-methionine + pyruvate 4-methylthio-2-oxobutanoate + L-alanine
Thus, the two substrates of this enzyme are D-methionine and pyruvate, whereas its two products are 4-methylthio-2-oxobutanoate and L-alanine.
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is D-methionine:pyruvate aminotransferase. Other names in common use include D-methionine transaminase, and D-methionine aminotransferase. This enzyme participates in d-alanine metabolism.
References
edit- Mapson LW, March JF, Wardale DA (1969). "Biosynthesis of ethylene. 4-methylmercapto-2-oxobutyric acid: an intermediate in the formation from methionine". Biochem. J. 115 (4): 653–61. PMC 1185190. PMID 5357015.
