Ávalos is a Spanish surname. Notable people with the surname include:
- Cristiano Ávalos dos Passos (born 1977), Brazilian footballer
- Enrique Tovar Ávalos, Mexican film director
- Fernando Horácio Ávalos (born 1978), Argentine footballer
- José Vicente Rangel Ávalos, the mayor of Sucre Municipality in Venezuela
- Juan de Ávalos (1911-2006), Spanish sculptor
- John Avalos (born 1964), American politician
- Johnny Avalos (born 1986), American serial killer
- Jorge Ramos Ávalos (born 1958), Mexican-American journalist and author.
- Luis Ávalos (1946–2014), Cuban actor
The d'Avalos were prominent in Renaissance Italy :
- Fernando d'Avalos (1489-1525), 5th Marquess of Pescara, won the Battle of Pavia
- Alfonso d'Avalos (1502-1546), Italian condottiero and 6th Marquess of Pescara
- Francesco Ferdinando d'Ávalos (1530–1571), 7th Marquess of Pescara