7-F-5-MeO-MET

5-MeO-7-F-MET
Identifiers
	IUPAC name N-ethyl-2-(7-fluoro-5-methoxy-1H-indol-3-yl)-N-methylethanamine;
PubChem CID	166157921;
Chemical and physical data
Formula	C14H19FN2O
Molar mass	250.317 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCN(C)CCC1=CNC2=C1C=C(C=C2F)OC;
	InChI InChI=1S/C14H19FN2O/c1-4-17(2)6-5-10-9-16-14-12(10)7-11(18-3)8-13(14)15/h7-9,16H,4-6H2,1-3H3; Key:IKYKXFMGTKYLAU-UHFFFAOYSA-N;

7-F-5-MeO-MET (5-MeO-7-F-MET, 5-Methoxy-7-fluoro-N-methyl-N-ethyltryptamine) is a tryptamine derivative which acts as a serotonin receptor agonist selective for the 5-HT₂ subtypes, with a pEC₅₀ of 8.71 at 5-HT_2A, vs 8.25 at 5-HT_2B and 7.69 at 5-HT_2C. In animal tests it produced the most potent head-twitch response of a range of related fluorinated tryptamine derivatives tested, though still with slightly lower potency than psilocybin.^[1]

References

^ WO 2022/256554, Wallach J, Dybek M, "Fluorinated Tryptamine Compounds, Analogues Thereof, and Methods Using Same", published 8 December 2022, assigned to University of the Sciences in Philadelphia.

[1] WO 2022/256554, Wallach J, Dybek M, "Fluorinated Tryptamine Compounds, Analogues Thereof, and Methods Using Same", published 8 December 2022, assigned to University of the Sciences in Philadelphia.

[1]

Identifiers

IUPAC name N-ethyl-2-(7-fluoro-5-methoxy-1H-indol-3-yl)-N-methylethanamine
PubChem CID	166157921
Chemical and physical data
Formula	C₁₄H₁₉FN₂O
Molar mass	250.317 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CCN(C)CCC1=CNC2=C1C=C(C=C2F)OC
InChI InChI=1S/C14H19FN2O/c1-4-17(2)6-5-10-9-16-14-12(10)7-11(18-3)8-13(14)15/h7-9,16H,4-6H2,1-3H3 Key:IKYKXFMGTKYLAU-UHFFFAOYSA-N

7-F-5-MeO-MET

See also

References