This article is an autobiography or has been extensively edited by the subject or by someone connected to the subject. (June 2020) |
Sir Brian Keith Follett FRS DL (born 22 February 1939) is a British biologist, academic administrator, and policy maker.[1][2] His research focused upon how the environment, particularly the annual change in day-length (photoperiod), controls breeding in birds and mammals. Knighted in 1992, he won the Frink Medal (1993) and has been a Fellow of the Royal Society since 1984, and served as the chair of the UK government's teacher training agency[3] and Arts and Humanities Research Council, and was Vice-Chancellor of University of Warwick.[4]
Sir Brian Follett FRS DL | |
|---|---|
| Born | 22 February 1939 (age 85) |
| Nationality | British |
| Alma mater | University of Bristol (BSc, PhD) |
| Known for | Vice-Chancellor of the University of Warwick 1993–2001; Chairman of the TDA (Training and Development Agency for Schools) 2003–2009; Chair of the Arts and Humanities Research Council (AHRC) 2001–2009; nonstipendiary professor Department of Zoology, University of Oxford 2001–2019. Professor and Chair, Biological Sciences, University of Bristol 1978–1993. |
| Awards | Elected to the Royal Society (1984) Frink Medal (1993), Zoological Society of London (ZSL) Scientific Medal (1976), Society of Endocrinology Dale Medal (1988) |
| Scientific career | |
| Fields | Zoology, biochemistry, seasonal breeding and clocks in birds and mammals |
| Institutions | University of Oxford (Department of Biology) |
Education and early life
editFollett was educated at Bournemouth School and studied biological chemistry. On graduating he undertook a Ph.D. with Professor Hans Heller in the Department of Pharmacology at the University of Bristol. That work introduced him to endocrinology and the development of assays to understand the physiological role of hormones.
Career and research
editIn 1964 Follett moved to Washington State University and joined Donald Farner's group investigating photoperiodism. His research focused on the brain pathways whereby birds (and mammals) measure day length and use these changes to change gonadotrophin secretion from the pituitary gland and so regulate breeding. He became a lecturer at Leeds University then moved with James Dodd FRS group to the University of Bangor in 1969, then to the University of Bristol in 1978.[citation needed]
He moved to Warwick in 1993 as Vice-Chancellor.[4]
Research programmes
editFollett's studies used, as model species, the Japanese quail and later wild-caught starlings. His work included the development of the first radioimmunoassay to measure bird luteinizing hormone (LH) in collaboration with Frank Cunningham (Reading University) and Colin Scanes.[5] This made it possible to measure LH in 10 microliters of plasma and so follow circulating hormone levels in individual birds exposed to photoperiods of many types. This enabled a detailed analysis of the annual pattern of hormone secretion as well as addresssing questions of especial importance. For example, using gonadectomized quail to show unequivocally that the underlying photoperiodic response in birds (but not mammals) is driven by brain circuits that are switched on and off by day length and to demonstrate that measuring day length involved a daily (circadian) rhythm in photosensitivity with the birds being responsive to light particularly between 12 and 18 hours after dawn. In other words, if light fell at these hours then the day was read as "long", if not then it was read as "short".
In 1978 as the Chair of Zoology at Bristol, his research interests expanded to include mammals, notably sheep, and wild birds such as albatrosses, swans, gulls and partridges. Key studies in this period included developing a rapid photoperiodic response system which enabled the detailed study of the neural pathways as they are switched on, the complex structure of ther time-measuring system and the action spectrum for the non-retinal light receptors (with Russell Foster). Subsequently, Takashi Yoshimura in Japan used the quail to investigate these changes in molecular terms and was able to connect these into the separate discoveries that thyroid hormones play a critical role in the photoperiodic response (see below). In Bristol the focus also swung towards the mechanisms involved in ending seasonal breeding - so-called refractoriness. The photoperiodic response involves both inducing breeding but also ending it. The Bristol group found, quite counterintuitively, that thyroid hormones are critical for refractoriness to develop and be maintained. This had been tentatively suggested in the Soviet Union prior to WWII but was developed by Trevor Nicholls, Arthur Goldsmith and Alistair Dawson. In simple terms, removal of the thyroid glands stopped refractoriness developing in starlings (and other birds) as well as sheep, and the animals remained in breeding condition perpetually and were not photorefractory. Thyroid hormone replacement reinstates the refractory state. Importantly birds are hatched in a refractory state but this is ended by removing the thyroid glands (per Tony Williams). The research group published papers on the concept which has now become established in the understanding of the photoneuroendocrine pathways in a wide range or organisms.
Funding came from the Agricultural and Food Research Council (AFRC), later renamed the Biotechnology and Biological Sciences Research Council (BBSRC), and Follett's group became an official Research Council Research Group on Photoperiodism and Reproduction, with 413 scientific papers and reviews.[6]
Academic administration
editFollett was Head of the Department of Zoology (later Biological Sciences) at the University of Bristol for fifteen years (1978–1993),[7] and Biological Secretary of the Royal Society from 1978 until 1993. He then served for eight years as Vice-Chancellor of the University of Warwick.[4] >
Follett was appointed to the Council of the AFRC/BBSRC and then to the UFC (Universities Funding Council) and its subsequent body – HEFCE (Higher Education Funding Council for England). He served on the Council of London Zoo (and Bristol Zoo) and as a Trustee of the Natural History Museum. He was elected to the Royal Society in 1984 and volunteered as the Biological Secretary for six years, making changes to the organisation and extending the Royal Society University Fellowship scheme. He was knighted in 1992.
In 1992 he was appointed to the Vice-Chancellorship at the University of Warwick and led it from 1993 until 2001. The University improved its ranking in the published league tables with strengths in Engineering (Warwick Manufacturing Group), Mathematics, Economics, Sociology and the Humanities. The Warwick Research Fellowships began as an annual £10m scheme in 1994, to attract the brightest young researchers in the UK and abroad. Success was seen in the Research Assessment Exercises of 1996 and 2001. £100m of capital building was undertaken. Warwick is a founding member of the Russell Group. It opened a graduate-entry medical school in 2001, President Clinton, with Prime Minister Blair, visited the university and gave a valedictory speech on foreign policy.[citation needed]
Follett has chaired committees for the UK government including reporting on the future of university libraries,[8] research in the humanities, and the foot-and-mouth outbreak of 2001;[9] and on the management and appraisal of clinical academics (following the AlderHey scandal).
Once retired, he took on the role of chair of the Arts and Humanities Research Council (2001–2009,[10] and chaired the government's Teacher Training Agency (TTA) and its successor body the Training and Development Agency for Schools (TDA) from 2004 to 2010. It aimed to resolve teacher training recruitment and to develop the concept of the teaching assistant. Follett was a non-stipendiary visiting professor in the Department of Biology, University of Oxford (2001–2019) and taught physiology to undergraduates. He was a governor of the Royal Shakespeare Theatre (2008–2018), and was president of the Stratford Civic Society.[11]
Honours
edit- Elected to the Royal Society in 1984.
- Knighted in 1992.
- Awarded 13 honorary doctorates and other awards.
Personal life
editFollet married Deb Booth, a teacher in 1961, who later worked in radio and as the production editor for the journals of the Society for Endocrinology. Their daughter Karen Williams is at BC Women's Hospital in Vancouver and is married to Tony Williams (Chair, School of Biology, Simon Fraser University). His son Richard Follett is an historian and is currently Vice-President and Deputy Vice-Chancellor (Global Engagement) at the University of Exeter.<ref>"Richard Follett," University of Exeter, accessed July 2024 (ref https://www.exeter.ac.uk/about/governance/managed/executive/
References
edit- ^ "Follett, Sir Brian (Keith)," Who's Who 2020, Oxford University Press, accessed June 3, 2020, https://doi.org/10.1093/ww/9780199540884.013.U16020
- ^ "Brian Follett". royalsociety.org. Retrieved 24 August 2023.
- ^ "Training and Development Agency for Schools annual report and accounts 2008 to 2009". GOV.UK. Retrieved 24 August 2023.
- ^ a b c "History". warwick.ac.uk. Retrieved 24 August 2023.
- ^ B.K.Follett, C.G. Scanes & F.J. Cunningham (1972). A radioimmunoassay for avian luteinizing hormone. J. Endocrinol. 52: 359–378.
- ^ Web of Science, https://app.webofknowledge.com/author/record/133782
- ^ "History of the School," School of Biological Sciences, University of Bristol, accessed June 3, 2020, http://www.bristol.ac.uk/media-library/sites/biology/documents/History%20of%20the%20School.pdf
- ^ "Joint Funding Council's Libraries Review Group: Report". www.ukoln.ac.uk. Retrieved 24 August 2023.
- ^ Infectious Diseases in Livestock, 2002. ISBN 0854035796)
- ^ James Herbert, Creating the AHRC (Oxford, UK: Oxford University Press, 2008) 100.
- ^ "Stratford Society". www.stratfordsociety.co.uk. Retrieved 24 August 2023.