Poghossian, Pogossyan, Poghosyan, Poghosian, Pogosyan, etc., (Armenian: Պողոսյան) is an Armenian surname. Also Ter-Pogossian, Der-Pogossian, and variants. Ter/Der indicates priesthood descent. The Western Armenian equivalent is Boghossyan. It is a patronymic from the first name Poghos (Armenian: Պողոս), equivalent to Paul, making the name effectively equivalent to Paulson. It may refer to:
- Armen Poghosyan, conductor of "Sofia" Russian private orchestra
- Armen Poghosyan (military musician), Armenian military musician
- David Pogosian, Olympic wrestler
- Gevorik Poghosyan, Armenian weightlifter
- Gilbert Pogosyan, American soccer player
- Hasmik Poghosyan, Minister of Culture of Armenia
- Manvel Ter-Pogosyan, a.k.a. Amurai, American trance music producer
- Metakse Poghosian, Armenian poet
- Michael Poghosyan, Armenian film and theatre actor and judge on the Armenian version of Pop Idol
- Mihran Poghosyan, Armenian businessman
- Mikhail Pogosyan, Russian aerospace engineer
- Ann Ter-Pogossian, American artist
- Michel Ter-Pogossian, American physicist
- Poghos Poghosyan, killed by President Kocharyan's bodyguards
- Sofya Poghosyan, Armenian broadcaster, psychologist and actress
- Stefan Pogosyan, Russian chess master
- Stepan Karapetovich Pogosyan
- Yura Poghosyan, a National Hero of Armenia
- Genrikh Poghosyan, Soviet party leader of the Nagorno-Karabakh Autonomous Oblast
- Zhirayr Poghosyan, Prime Minister of Nagorno-Karabakh