Jōetsu (上越) may refer to:
- as Kami-Echigo (上越後):
- Jōetsu region, a geographical region in Niigata Prefecture
- Jōetsu, Niigata, a city in Niigata Prefecture, Japan
- Jōetsumyōkō Station, a railway station in Jōetsu, Niigata
- as Kōzuke (上野) and Echigo (越後):
- Jōetsu Line, a major rail line in Japan
- Jōetsu Shinkansen, a high-speed shinkansen railway line connecting Tokyo and Niigata