Isopropamide (R79) is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders involving hyperacidity (gastrointestinal acidosis) and hypermotility.[citation needed] Chemically, it contains a quaternary ammonium group. It is most often provided as an iodide salt, but is also available as a bromide or chloride salt. It was discovered at Janssen Pharmaceutica in 1954.[citation needed]
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MedlinePlus | a694006 |
Routes of administration | Oral |
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ECHA InfoCard | 100.028.470 |
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Formula | C23H33N2O+ |
Molar mass | 353.530 g·mol−1 |
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References
editFurther reading
edit- Seeherman R (October 1957). "Isopropamide iodide: a long-acting anticholinergic". Delaware Medical Journal. 29 (10): 265–9. PMID 13473394.
- Boss Jr EG, Buchanan GC (November 1957). "Effect of isopropamide iodide on basal gastric secretion in the human". Gastroenterology. 33 (5): 730–6. doi:10.1016/S0016-5085(19)35625-2. PMID 13480414.