Haematin (also known as hematin, ferriheme, hematosin, hydroxyhemin, oxyheme, phenodin, or oxyhemochromogen) is a dark bluish or brownish pigment containing iron in the ferric state, obtained by the oxidation of haem.[1]
Haematin inhibits the synthesis of porphyrin (by repressing ALAS1 synthesis),[2] and stimulates the synthesis of globin. For this reason, it is used in the treatment of porphyrias.[2]
It is a component of cytochromes and peroxidases. Haematin derived synthetically from hemin is used as a reagent.[3]
References
edit- ^ "haematin. (n.d.) Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. (2003). Retrieved December 17 2015".
{{cite journal}}: Cite journal requires|journal=(help) - ^ a b Rodwell, Victor W. (2018). Harper's Illustrated Biochemistry (31st ed.). McGraw-Hill Education. p. 311. ISBN 978-1-25-983794-4.
- ^ "haematin. (n.d.) Dorland's Medical Dictionary for Health Consumers. (2007). Retrieved December 17 2015".
{{cite journal}}: Cite journal requires|journal=(help)
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